The pipeline

Every idea, tracked in the open

Each entry below is an idea with a hypothesis, a stage, and a signal. Interactive ideas ship as applications; static ideas ship as writing. Low-signal ideas cycle back into the foundry with what we learned.

Shipped

Prototypes that earned their way out — live and generating value.

PR-004▤ static · Blog

Leading with Attention

Lessons from AI software engineering translate directly into how technical teams should be led.

Shipped

▲ Live on Medium — recurring series

Evaluating

Being measured against their hypothesis right now.

PR-000◇ interactive · Application

Perrin Research

A public site that explains the foundry operating model and pipeline can attract collaborators and validate the portfolio thesis.

Evaluating

▲ Live at dev.perrinresearch.com — production at perrinresearch.com

PR-002◇ interactive · Application

Waypoint

Portfolio surveillance focused on a sector or disease area surfaces where capital and science converge before the market does.

Evaluating

▲ Working prototype — daily internal use

PR-008◇ interactive · Application

Foundry

A central site for project intake, task tracking, and prompt ideas would drive development.

Evaluating
In the foundry

Prototype

Under active workup — agents and humans building the artifact.

PR-001◇ interactive · Application

Restore79

Dystrophin and muscle models plus financial disease-cost models can change how Duchenne therapies are valued.

Prototype

▲ Strong domain pull — active build

PR-005▤ static · Blog

Muscle, Exercise, & Dystrophinopathy

Families navigating Duchenne need a clear, evidence-based account of muscle, exercise, and plasticity.

Prototype

▲ Drafts in evaluation

In the foundry
PR-007◇ interactive · Application

Evaluation Plugin

Framework for evaluating prototypes.

Prototype
In the foundry

Idea

Captured as hypotheses, queued for agent workup.

PR-006▤ static · Blog

Built to Change

Gaming muscle plasticity for lasting mobility is a book-scale idea — too big for a post, too useful to stay unwritten.

Idea

▲ Chapters in prototype

In the foundry