Leading with Attention
Lessons from AI software engineering translate directly into how technical teams should be led.
▲ Live on Medium — recurring series
Perrin Research · Idea Foundry
We translate ideas into working prototypes, measure them for value, and ship the ones that earn it. Interactive ideas become applications. Static ideas become writing. AI agents run the loop.
The operating model
Nothing ships on opinion. Ideas become prototypes, prototypes generate evidence, and the evidence decides.
If the idea is interactive
it becomes an application
web apps · models · tools
If the idea is static
it becomes writing
essays · articles · books
Powered by AI agents
AI agents are the machinery of the foundry. They work up prototypes, run evaluations, and cycle ideas through the loop far faster than a traditional lab — so more ideas get a fair test, and only the valuable ones consume real time.
Now in the pipeline
8 prototypes tracked · 7 in flight · 1 shipped
Lessons from AI software engineering translate directly into how technical teams should be led.
▲ Live on Medium — recurring series
A public site that explains the foundry operating model and pipeline can attract collaborators and validate the portfolio thesis.
▲ Live at dev.perrinresearch.com — production at perrinresearch.com
Portfolio surveillance focused on a sector or disease area surfaces where capital and science converge before the market does.
▲ Working prototype — daily internal use
Raw material
Prototypes are only as good as the domain depth behind them. Ours comes from four places.
Machine learning and agentic systems — both the subject of our work and the machinery that runs the foundry.
Duchenne and related conditions, from molecular models to exercise science and patient impact.
Translational insight connecting biological mechanism to therapeutic and economic outcomes.
Computational modeling of proteins, membranes, and molecular systems at atomistic scale.
The bet
Most organizations decide what to build, then build it. We build first — cheaply, with agents — and let measured value decide what deserves to exist. This site, like everything we make, is a prototype that earned its place.